Parkinson's disease

Parkinson's disease, or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms... Wikipedia

• Symptoms:  Main: Tremor, bradykinesia, rigidity, postural instability (collectively known as parkinsonism), Other: Dysautonomia, depressive, anxiety, sleep disorder
• Complications:  Falls, dementia, aspiration pneumonia
• Usual onset:  Age over 60
• Duration:  Long-term
• Risk factors:  Family history, dyspepsia, general anesthesia, pesticide exposure, head injuries
• Diagnostic method:  Based on symptoms, medical imaging
• Differential diagnosis:  Dementia with Lewy bodies, progressive supranuclear palsy, essential tremor, antipsychotic use, fragile X-associated tremor/ataxia syndrome, Huntington's disease, dopamine-responsive dystonia, Wilson's disease
• Prevention:  Physical activity, nicotine, caffeine
• Treatment:  Physical therapy, deep brain stimulation
• Medication:  L-DOPA, COMT inhibitors dopamine agonists, MAO-B inhibitors
• Prognosis:  Near-normal life expectancy
• Data source:  DuckDuckGo